Take one part creativity, one part local foods, and one part Southern hospitality, and you've got the Tupelo Honey Cafe. Opened in downtown in 2000, Tupelo supports more than 25 farms and artisanal food purveyors while offering up funky takes on regional dishes like honey chipotle wings, Appalachian egg rolls, smoked jalapeƱo BBQ sauce, and fried green tomatoes. Whether you stop in their original, Knoxville, or Southside locations, you can also take a piece of Tupelo home with you with a copy of their cookbook.