Sometimes you go to a museum to view the art inside. But sometimes the museum itself is a work of art. As it is with the Tampa Museum of Art. Set along the Hillsborough River, this striking Stanley Saitowitz design opened in 2010 and has won numerous awards in short time since; it's also home to Leo Villareal's Sky, an installation of LEDs that covers 14,000 square feet of facade and lights up the building after dark. Of course, you still want to see what's on the inside, and will be happy to find a impressive permanent collection of modern and contemporary art, along with Greek and Roman antiquities. Pair with the nearby Dalí Museum for a day full of amazing art and architecture.