Sure, the home of Yale isn't the first place we think of when we think of great pizza — but any list of the Northeast's best pies needs to include Frank Pepe Pizzeria Napoletana. Established in 1925 and operating out of the same building since 1937, Pepe's cooks their pizzas in a coal-fired bread oven, giving the thin crust pizzas a unique char. So what should you order? We'd recommend getting the signature White Clam Pizza, topped with littleneck clams, garlic, cheese, olive oil, and oregano, which is original as the place itself.